SHKBP1 antibody

Catalog No. ABIN7119029

The Rabbit Polyclonal anti-SHKBP1 antibody has been validated for WB, ELISA and IF. It is suitable to detect SHKBP1 in samples from Human, Mouse and Rat.

Quick Overview for SHKBP1 antibody (ABIN7119029)

Target: SHKBP1 (Sh3kbp1 Binding Protein 1 (SHKBP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SHKBP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-SHKBP1 Antibody

Purpose: SHKBP1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: SH3KBP1 binding protein 1

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for SHKBP1

Target: SHKBP1 (Sh3kbp1 Binding Protein 1 (SHKBP1))

Alternative Name: SHKBP1

Background:

Synonyms: SH3KBP1-binding protein 1|SETA-binding protein 1|SHKBP1|SB1

Background: Inhibits CBL-SH3KBP1 complex mediated down-regulation of EGFR signaling by sequestration of SH3KBP1. Binds to SH3KBP1 and prevents its interaction with CBL and inhibits translocation of SH3KBP1 to EGFR containing vesicles upon EGF stimulation.

Molecular Weight: 76 kDa

Gene ID: 92799

UniProt: Q8TBC3